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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
GPIX_HUMAN
USC-OGP 2-DE database
:
GPIX_HUMAN
GPIX_HUMAN
General information about the entry
View entry in simple text format
Entry name
GPIX_HUMAN
Primary accession number
P14770
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Platelet glycoprotein IX; Short=GP-IX; Short=GPIX; AltName: Full=Glycoprotein 9; AltName: CD_antigen=CD42a; Flags: Precursor;.
Gene name
Name=GP9
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-5
{PLATELET 4-5}
Homo sapiens (Human)
map experimental info
PLATELET_4-5
MAP LOCATIONS:
SPOT OGP-0234
:
pI=4.45; Mw=19089
Cross-references
UniProtKB/Swiss-Prot
P14770; GPIX_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
GPIX_HUMAN
Primary accession number
P14770
Secondary accession number(s)
Q14445 Q8N1D1 Q92525
Sequence was last modified on
November 1, 1997 (version 3)
Annotations were last modified on
March 15, 2017 (version 175)
Name and origin of the protein
Description
RecName: Full=Platelet glycoprotein IX; Short=GP-IX; Short=GPIX; AltName: Full=Glycoprotein 9; AltName: CD_antigen=CD42a; Flags: Precursor;
Gene name
Name=GP9
Encoded on
Name=GP9
Keywords
3D-structure
;
Bernard Soulier syndrome
;
Blood coagulation
;
Cell adhesion
;
Complete proteome
;
Direct protein sequencing
;
Disease mutation
;
Disulfide bond
;
Glycoprotein
;
Hemostasis
;
Leucine-rich repeat
;
Membrane
;
Reference proteome
;
Signal
;
Transmembrane
;
Transmembrane helix
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X52997; CAA37186.1
; -; mRNA
EMBL
M80478; AAB40042.1
; -; Genomic_DNA
EMBL
M25827; AAA36809.1
; -; mRNA
EMBL
BC030229; AAH30229.1
; -; mRNA
EMBL
D88290; BAA13580.1
; -; Genomic_DNA
CCDS
CCDS3055.1; -
; .
PIR
A46606; A46606
; .
RefSeq
NP_000165.1; NM_000174.4
; .
RefSeq
XP_005247431.1; XM_005247374.3
; .
RefSeq
XP_011511003.1; XM_011512701.1
; .
RefSeq
XP_011511004.1; XM_011512702.1
; .
UniGene
Hs.1144; -
; .
PDB
3REZ; X-ray
; 2.35 A; A/B/C/D=45-52
A/B/C/D=65-76
A/B/C/D=92-102; PDBsum; 3REZ; -
ProteinModelPortal
P14770; -
; .
SMR
P14770; -
; .
BioGrid
109077; 4
; .
IntAct
P14770; 22
; .
MINT
MINT-6742784; -
; .
STRING
9606.ENSP00000303942; -
; .
DrugBank
DB00468; Quinine
; .
iPTMnet
P14770; -
; .
PhosphoSitePlus
P14770; -
; .
BioMuta
GP9; -
; .
DMDM
2822110; -
; .
OGP
P14770; -
; .
PaxDb
P14770; -
; .
PeptideAtlas
P14770; -
; .
PRIDE
P14770; -
; .
DNASU
2815; -
; .
Ensembl
ENST00000307395; ENSP00000303942
; ENSG00000169704; .
GeneID
2815; -
; .
KEGG
hsa:2815; -
; .
UCSC
uc003elm.3; human
; .
CTD
2815; -
; .
DisGeNET
2815; -
; .
GeneCards
GP9; -
; .
HGNC
HGNC:4444; GP9
; .
HPA
HPA063182; -
; .
MalaCards
GP9; -
; .
MIM
173515; gene
; .
MIM
231200; phenotype
; .
neXtProt
NX_P14770; -
; .
OpenTargets
ENSG00000169704; -
; .
Orphanet
274; Bernard-Soulier syndrome
; .
PharmGKB
PA28825; -
; .
eggNOG
KOG0619; Eukaryota
; .
eggNOG
COG4886; LUCA
; .
GeneTree
ENSGT00530000064244; -
; .
HOGENOM
HOG000089943; -
; .
HOVERGEN
HBG005898; -
; .
InParanoid
P14770; -
; .
KO
K06263; -
; .
OMA
CTCQALE; -
; .
OrthoDB
EOG091G0XGH; -
; .
PhylomeDB
P14770; -
; .
Reactome
R-HSA-140837; Intrinsic Pathway of Fibrin Clot Formation
; .
Reactome
R-HSA-430116; GP1b-IX-V activation signalling
; .
Reactome
R-HSA-75892; Platelet Adhesion to exposed collagen
; .
Reactome
R-HSA-76009; Platelet Aggregation (Plug Formation)
; .
GeneWiki
Glycoprotein_IX; -
; .
GenomeRNAi
2815; -
; .
PRO
PR:P14770; -
; .
Proteomes
UP000005640; Chromosome 3
; .
Bgee
ENSG00000169704; -
; .
CleanEx
HS_GP9; -
; .
Genevisible
P14770; HS
; .
GO
GO:0005887; C:integral component of plasma membrane
; TAS:ProtInc; .
GO
GO:0005886; C:plasma membrane
; TAS:Reactome; .
GO
GO:0007596; P:blood coagulation
; TAS:Reactome; .
GO
GO:0007597; P:blood coagulation
; intrinsic pathway; TAS:Reactome
GO
GO:0007155; P:cell adhesion
; NAS:ProtInc; .
GO
GO:0030168; P:platelet activation
; TAS:Reactome; .
Gene3D
3.80.10.10; -
; 1; .
InterPro
IPR000483; Cys-rich_flank_reg_C
; .
InterPro
IPR032675; L_dom-like
; .
InterPro
IPR001611; Leu-rich_rpt
; .
InterPro
IPR000372; LRRNT
; .
Pfam
PF13855; LRR_8
; 1; .
Pfam
PF01462; LRRNT
; 1; .
SMART
SM00082; LRRCT
; 1; .
SMART
SM00013; LRRNT
; 1; .
SUPFAM
SSF52058; SSF52058
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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