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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: GPIX_HUMAN




USC-OGP 2-DE database:  GPIX_HUMAN


GPIX_HUMAN


General information about the entry
View entry in simple text format
Entry nameGPIX_HUMAN
Primary accession numberP14770
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Platelet glycoprotein IX; Short=GP-IX; Short=GPIX; AltName: Full=Glycoprotein 9; AltName: CD_antigen=CD42a; Flags: Precursor;.
Gene nameName=GP9
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-5 {PLATELET 4-5}
Homo sapiens (Human)
PLATELET_4-5
  map experimental info
 
PLATELET_4-5

MAP LOCATIONS:
pI=4.45; Mw=19089

Cross-references
UniProtKB/Swiss-ProtP14770; GPIX_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameGPIX_HUMAN
Primary accession numberP14770
Secondary accession number(s) Q14445 Q8N1D1 Q92525
Sequence was last modified on November 1, 1997 (version 3)
Annotations were last modified on March 15, 2017 (version 175)
Name and origin of the protein
DescriptionRecName: Full=Platelet glycoprotein IX; Short=GP-IX; Short=GPIX; AltName: Full=Glycoprotein 9; AltName: CD_antigen=CD42a; Flags: Precursor;
Gene nameName=GP9
Encoded onName=GP9
Keywords3D-structure; Bernard Soulier syndrome; Blood coagulation; Cell adhesion; Complete proteome; Direct protein sequencing; Disease mutation; Disulfide bond; Glycoprotein; Hemostasis; Leucine-rich repeat; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX52997; CAA37186.1; -; mRNA
EMBLM80478; AAB40042.1; -; Genomic_DNA
EMBLM25827; AAA36809.1; -; mRNA
EMBLBC030229; AAH30229.1; -; mRNA
EMBLD88290; BAA13580.1; -; Genomic_DNA
CCDSCCDS3055.1; -; .
PIRA46606; A46606; .
RefSeqNP_000165.1; NM_000174.4; .
RefSeqXP_005247431.1; XM_005247374.3; .
RefSeqXP_011511003.1; XM_011512701.1; .
RefSeqXP_011511004.1; XM_011512702.1; .
UniGeneHs.1144; -; .
PDB3REZ; X-ray; 2.35 A; A/B/C/D=45-52
A/B/C/D=65-76A/B/C/D=92-102; PDBsum; 3REZ; -
ProteinModelPortalP14770; -; .
SMRP14770; -; .
BioGrid109077; 4; .
IntActP14770; 22; .
MINTMINT-6742784; -; .
STRING9606.ENSP00000303942; -; .
DrugBankDB00468; Quinine; .
iPTMnetP14770; -; .
PhosphoSitePlusP14770; -; .
BioMutaGP9; -; .
DMDM2822110; -; .
OGPP14770; -; .
PaxDbP14770; -; .
PeptideAtlasP14770; -; .
PRIDEP14770; -; .
DNASU2815; -; .
EnsemblENST00000307395; ENSP00000303942; ENSG00000169704; .
GeneID2815; -; .
KEGGhsa:2815; -; .
UCSCuc003elm.3; human; .
CTD2815; -; .
DisGeNET2815; -; .
GeneCardsGP9; -; .
HGNCHGNC:4444; GP9; .
HPAHPA063182; -; .
MalaCardsGP9; -; .
MIM173515; gene; .
MIM231200; phenotype; .
neXtProtNX_P14770; -; .
OpenTargetsENSG00000169704; -; .
Orphanet274; Bernard-Soulier syndrome; .
PharmGKBPA28825; -; .
eggNOGKOG0619; Eukaryota; .
eggNOGCOG4886; LUCA; .
GeneTreeENSGT00530000064244; -; .
HOGENOMHOG000089943; -; .
HOVERGENHBG005898; -; .
InParanoidP14770; -; .
KOK06263; -; .
OMACTCQALE; -; .
OrthoDBEOG091G0XGH; -; .
PhylomeDBP14770; -; .
ReactomeR-HSA-140837; Intrinsic Pathway of Fibrin Clot Formation; .
ReactomeR-HSA-430116; GP1b-IX-V activation signalling; .
ReactomeR-HSA-75892; Platelet Adhesion to exposed collagen; .
ReactomeR-HSA-76009; Platelet Aggregation (Plug Formation); .
GeneWikiGlycoprotein_IX; -; .
GenomeRNAi2815; -; .
PROPR:P14770; -; .
ProteomesUP000005640; Chromosome 3; .
BgeeENSG00000169704; -; .
CleanExHS_GP9; -; .
GenevisibleP14770; HS; .
GOGO:0005887; C:integral component of plasma membrane; TAS:ProtInc; .
GOGO:0005886; C:plasma membrane; TAS:Reactome; .
GOGO:0007596; P:blood coagulation; TAS:Reactome; .
GOGO:0007597; P:blood coagulation; intrinsic pathway; TAS:Reactome
GOGO:0007155; P:cell adhesion; NAS:ProtInc; .
GOGO:0030168; P:platelet activation; TAS:Reactome; .
Gene3D3.80.10.10; -; 1; .
InterProIPR000483; Cys-rich_flank_reg_C; .
InterProIPR032675; L_dom-like; .
InterProIPR001611; Leu-rich_rpt; .
InterProIPR000372; LRRNT; .
PfamPF13855; LRR_8; 1; .
PfamPF01462; LRRNT; 1; .
SMARTSM00082; LRRCT; 1; .
SMARTSM00013; LRRNT; 1; .
SUPFAMSSF52058; SSF52058; 1; .



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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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